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The result: more efficient use of fat as a fuel, especially when demand is high (e.g., exercise)
In diseases characterized by chronic ER stress, such as diabetes and neurodegenerative disorders, modulating the UPR and autophagy could provide therapeutic benefits
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Among the differentially expressed genes, 58 modules were identified as closely associated with microglial GLP-1R pathways and features of nerve injury, including pain hypersensitivity, ligation, paw withdrawal latency, and anxiety-related behaviors [64]
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