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Semaglutide is a long-acting GLP-1 (glucagon-like peptide-1) receptor agonist, structurally modified from native GLP-1 with a fatty-acid side chain that enables reversible albumin binding extending its half-life to approximately one week and enabling once-weekly dosing regimens studied extensively in clinical trials

Kobori, T., Onishi, Y., Yoshida, Y., Tahara, T., Kikuchi, T., Kubota, T., Iwamoto, M., Sawada, T., Kobayashi, R., Fujiwara, H., & Kasuga, M

Protocol cycling decisions, including continuous vs paused, are determined at the consultation based on IGF-1 response and treatment goals

Eli Lilly and Novo Nordisk now offer savings programs that can significantly reduce out-of-pocket costs, even for patients without insurance