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Most people who begin taking one lose anywhere between 6-17% of their body weight, and some newer versions of these medications may lead to weight loss of as much as 25%
These are relatively mild compared to pharmaceutical GLP-1 medications, which commonly cause significant nausea, vomiting, diarrhea, constipation, and in rare cases more serious effects including pancreatitis and thyroid concerns
J Neurosci Res (2011) 89(4):4819
Saxenda (liraglutide) : Earlier-generation GLP-1 medication showing approximately 8% weight loss over 56 weeks in clinical trials
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