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GLP-1 drugs (exenatide, liraglutide etc), as well as GIP/GLP-1 hybrid peptides (tirzepatide), are clinically approved for diabetes and/or obesity, with GLP-2 based drugs (teduglutide) approved for the treatment of short bowel syndrome
10.1074/jbc.M116.722744 J
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The extensor digitorum longus muscles were carefully dissected from WT and VECAD IGF- 1R KD mice while continuously superfused with oxygenated KrebsHenseleit buffer (95% O, 5% CO, pH 7.4, 37 C) to maintain physiological conditions
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