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By contrast, those with established cardiovascular disease already on aspirin are described as typically safe to begin GLP-1 therapy
A 2025 study published in Obesity found that GLP1 users lost 7.7% of body weight on semaglutide and 12.4% on tirzepatide after one year, roughly half the weight loss seen in randomized trials
Depending on health history and certain conditions, some patients will require labs to continue treatment
In addition, scientists continue to explore its role in melanocortin research and related biological functions
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