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Weight loss resistance may involve: Insulin resistance Thyroid dysfunction Low testosterone Menopause-related hormone shifts High stress and cortisol disruption Poor sleep or sleep apnea Chronic inflammation Nutrient deficiencies Medication-related weight gain Loss of muscle mass Gut health problems Emotional eating or reward-based eating patterns A GLP-1 medication may help appetite, but it may not fully correct these other issues
Fallon RF, Goodenough DA
Whether that produces a meaningfully different result depends on the individual
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