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TXNIP downregulates V-maf musculoaponeurotic fibrosarcoma oncogene homolog A (MafA), a transcription factor to drive insulin expression, and thus negatively regulates insulin expression 25

Keytruda (pembrolizumab) , Mercks PD-1 inhibitor and the worlds best-selling drug, faces a more complex biosimilar landscape given both the biological complexity of the molecule and the strength of its label spanning more than 30 tumor types [38]

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Some individuals may also experience changes in blood sugar levels