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Cells were washed three times with RPMI1640 medium and incubated with 1 g ml 1 Alexa Fluor 594 goat anti-rat IgG (HL) for 5 min at 4 C
Confavreux, C
An increased ratio of succinate to -KG in cancers resulting from impaired succinate dehydrogenase (SDH) activity is related to pervasive DNA hypermethylation, which contributes to the downregulation of key genes implicated in cell differentiation and cancer stages 102
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