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Comprehensive nutritional strategies complement injectable therapy by ensuring the body has adequate raw materials for glutathione production while reducing oxidative burdens that deplete glutathione reserves

BSO treatment showed increased expression of Dnmt3a and 3b and decreased Tet2 and 3 transcripts, and it was not wholly restored after treatment withdrawal at different time points, as was shown by real-time PCR analyses (Fig

Because cLip-1 accumulates in lysosomes and contains nitrogen atoms susceptible to interactions with iron, we investigated the possibility that its ferroptosis inhibition properties can result from iron inactivation in this organelle

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