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In theory, degraded peptide fragments could potentially trigger antibody formation at a higher rate than intact semaglutide
However, in the complex molecular processes that characterize tumorigenesis, iron also plays a central role in ferroptosis, a form of non-apoptotic regulated cell death characterized by the lethal accumulation of lipid peroxidation products and ROS derived from iron metabolism (362, 363)
Volinia et al., 2006
POPs are mainly excreted through conjugation with GSH and this mechanism is extremely important for the health status, since exposure to POPs has been associated to diabetes, cardiovascular diseases and many other chronic diseases ( ROS production can occur at several intracellular sites but, for most cells, takes place in the mitochondria and the mitochondrial electron transport chain is the main cellular process of ROS generation in physiological circumstances ( 2 O 2 )
