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Alpha-1 and alpha-2 receptor stimulation causes peripheral vasoconstriction, increases blood pressure, and reduces mucosal and vascular edema

The Phase 1 study (NCT04674306), conducted at Cleveland Clinics Main Campus in partnership with Anixa Biosciences, Inc., included 35 patients across three cohorts: Launched in 2021, the trial enrolled 26 patients in Phase 1a, four in Phase 1b, and five in Phase 1c