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The maternal immune response to fetal platelet GPIb causes frequent miscarriage in mice that can be prevented by intravenous IgG and anti-FcRn therapies
More significantly, MOTS-c administration shifted the trajectory of age-related metabolic decline, indicating that the peptide's benefits are not limited to preventing dysfunction in young animals but can partially reverse established decline [2]
Several studies have explored the utilization of RWD in conducting clinical trials 1,2,3,4 , providing external control groups for single-arm studies 5,6 , and complementing the control group in randomized controlled trials (RCTs) 7,8,9
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