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That said, Katz offers the following general guidelines: Magnesium glycinate (for sleep and relaxation): 100 to 200 milligrams of elemental magnesium, though some people may benefit from slightly higher doses Magnesium citrate: 150 to 300 milligrams of elemental magnesium ("Higher doses increase the likelihood of a laxative effect," Katz notes.) Before starting a new supplement, it's always a good idea to check with your health-care provider especially if you have underlying health conditions or take medications

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Key questions to discuss include: Whether you meet NHS criteria for GLP-1 prescription (type 2 diabetes or obesity with complications) The evidenceor lack thereoffor GLP-1 use specifically in Hashimoto's management Potential interactions between GLP-1 medications and thyroid hormone replacement How GLP-1 therapy might affect your thyroid function monitoring schedule Alternative evidence-based approaches to managing metabolic symptoms in Hashimoto's The costs and practicalities of private prescription if NHS funding is not available Contraception requirements if you are of childbearing potential (GLP-1 medications should be avoided in pregnancy and breastfeeding) Your GP may recommend optimising your current thyroid management first , ensuring your levothyroxine dose is appropriate and that you are not over- or under-replaced