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This is not specific to tirzepatide or AOD 9604 but rather a consequence of rapid weight loss itself, known as telogen effluvium
These non-selective effects create cardiovascular stress and uncomfortable side effects
The zero withdrawal rate in AOD-9604 trials suggests excellent practical tolerability that extends beyond merely counting adverse events to assessing their real impact on treatment continuation
Based on the clinical trial data and the known mechanism, AOD 9604 does not appear to cause muscle loss
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