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The review highlights data from randomized controlled trials and meta-analyses that demonstrate reductions in both apnea-hypopnea index (AHI) and body weight among patients treated with GLP-1RA and dual GLP-1 and glucose-dependent insulinotropic peptide (GIP) receptor agonists
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However, these lipid changes were generally considered secondary outcomes rather than primary endpoints
Rather than replacing earlier peptides, each new generation gives researchers another way to explore the complexity of metabolic biology
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