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An earlier paper on the trial also gave no details about the placebo (Ref 7)
Metabolomics was utilized to analyze obesity-related metabolites in kidney samples
Lifestyle optimization: Maximizing NAD+ naturally Beyond supplementation, certain lifestyle factors can naturally support NAD+ levels: High-intensity interval training (HIIT) increases NAD+ more effectively than steady-state cardio
1 The findings showed: Those not taking GLP-1 medications showed significantly more MS disease progression Higher risk of brainstem dysfunction (4.36% risk difference) Higher risk of cerebellar dysfunction (4.54% risk difference) Higher risk of bowel and bladder dysfunction (4.98% risk difference) As a retrospective analysis, this study has limitations including potential confounding factors, and definitive randomised controlled trials are needed to confirm any disease-modifying effects of GLP-1 medications in MS
