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Signs of effective DSIP use include: easier time falling asleep, fewer nighttime awakenings, feeling more refreshed upon waking, improved daytime energy and mood, better stress tolerance, and enhanced recovery from physical activity
defined primary cerebral folate deficiency as a neurological syndrome associated with normal levels of extraneurological folate but reduced levels of 5-methyltetrahydrofolate (5MTHF), a folate metabolite in cerebrospinal fluid [101]
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Excessive ROS production beyond self-regulation processes leads to irreversible damage to cellular function or death (Rotariu et al., 2022)
