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Research on GLP-1 receptor agonists (the parent class of tirzepatide) shows that nutrient deficiencies are rare during treatment, but they can develop over time if baseline levels are low or if intake decreases due to reduced appetite
The ideal candidate is a patient who has hit a hard plateau on a GLP-1 receptor agonist and complains of significant fatigue or lethargy
Others schedule maintenance to help keep levels steady, especially if they follow a plant-forward diet, take certain medications that affect absorption, or have a history of deficiency
J., Van Der Wal, G., & Ferrier, M
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