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The active ingredient in milk thistle extract is Silybum marianum, which is actually the collective name for three distinct compounds
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Possible side effects Mild allergic or skin reactions in sensitive individuals Possible lowering of zinc levels with overuse Interactions if combined with other, undisclosed supplements With unsupervised or high-dose IV use, more serious reactions have been reported Regulatory context you should know IV glutathione is widely marketed for whitening, but it is used off-label for this purpose
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