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Signal 15 , eabn2707 (2022)
However, when the investigational drug presents a higher level of risk for example in certain oncology settings, where the compound may be too toxic for healthy subjects the study may involve patients instead
Mostajeran F, Tehrani HG, Rahbary B
Complications of Polypharmacy Polypharmacy can lead to several problems, including adverse drug events (ADEs), inappropriate medication uses in the elderly, drug interactions, higher treatment costs, more hospitalizations, and increased mortality
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