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Oxalic acid is known for its nephrotoxic potential and mitochondriadisrupting effects, and it often accumulates under conditions of gut dysbiosis, vitamin B6 deficiency, or impaired glyoxylate metabolism

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The study conducted by Li Meihe demonstrates that trophoblast ferroptosis is a key contributor to miscarriage, which is regulated through oxidative stress and activation of the Nod-Like Receptor Protein (NLRP1) inflammasome

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doi: 10.1038/s41392-024-01931-z 23

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