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At the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) 2025 Annual Meeting and Trainee Symposium, investigators with the GRAPPA dove into hours worth of discussions and debates about a class of drugs whose emergence Artie Kavanaugh, MD, professor of medicine at the University of California, San Diego, described as a possible watershed moment for the field, akin to the advent of biologic therapies in the 1990s
Xanthine oxidoreductase is a rate-limiting enzyme catalyzing formation of UA by oxidative hydroxylation of hypoxanthine and xanthine in purine metabolism (Nakatani et al., 2021)
It feels like a leap of faith and you're kind of a guinea pig," she said
Wegovy contains semaglutide and Zepbound contains tirzepatide, both approved for chronic weight management in eligible adults
