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Patients with diabetes for more than 5 years show a higher prevalence compared with those diagnosed more recently [6]

Future research should focus on developing more specific ferroptosis inducers, elucidating the crosstalk between ferroptosis and the tumor microenvironment, establishing predictive biomarker systems based on ferroptosis-related mechanisms, and further optimizing combination treatment regimens and dosing strategies

In early work, a hairpin pyrrole-imidazole polyamide was designed to target the ARE to disrupt AR DBD binding and was effective at inhibiting androgen-induced PSA expression in LNCaP cells 181

Graziani, G