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333 AG-270 is an oral selective MAT2A inhibitor that selectively inhibits the proliferation of MTAP null cells and effectively reduces the level of SAM in tumor cells in tissue and xenograft tumor models

doi: 10.1038/s41467-024-47594-w 86 HuY.HeJ.MaY.GeL.LouB.FangX.et al

It is known as a selective growth hormone secretagogue which operates by mimicking the ghrelin receptor, a hormone that stimulates the release of growth hormone (GH)