does semaglutide affect kidneys significant 24% reduction in kidney disease progression and death related to kidney and cardiovascular causes in those treated with compared to a placebo does semaglutide affect kidney function

doi: 10.1172/jci.insight.133429 Summary Keywords GLP-1 receptor agonists, type 2 diabetes, eating behavior, weight loss, personalized medicine Citation Koide Y, Kato T, Hayashi M, Daido H, Maruyama T, Ishihara T, Nishimura K, Tsunekawa S and Yabe D (2025) Association between eating behavior patterns and the therapeutic efficacy of GLP-1 receptor agonists in individuals with type 2 diabetes: a multicenter prospective observational study

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doi: 10.1111/joim.13049, 142

Engineered as a synthetic peptide based on the native GIP sequence and modified for extended half-life via fatty acid conjugation, tirzepatide delivers glycemic control, profound weight loss, and cardiometabolic benefits