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Wegovy and Saxenda, both injectables, are the only GLP-1s FDA-approved for obesity
Key Points Nitric oxide (NO), a diatomic free radical gas, is generated by NO synthases (NOSs) in tissues to regulate a multitude of physiological processes, most notably cardiovascular function
Nobiletin is a polymethoxylated flavonoid isolated from citrus fruits that exhibits a wide range of physiological effects
Long-term studies have shown even more significant reductions, with weight loss continuing over 48 weeks
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