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The goal is smoother drug levels (lower peaks, higher troughs), which can reduce the nausea spike that hits 1-2 days after a full weekly injection
This can lead to reduced expression of GLP- 1 receptors and the development of GLP- 1 resistance
If you want a more detailed walkthrough, this reconstitution guide for 10 mg tirzepatide covers the same core process in more depth
Day 45: I could walk to the local shop without stopping to catch my breath
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