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Description

The popularity of these drugs led to significant shortages, prompting the FDA to allow compounded versions to be produced by smaller pharmacies

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The mentioned DPP-4 inhibitors are orally active, rapidly absorbed, and suitable for once daily or twice daily administration, leading to a DPP-4 inhibition of 7090% over 24 h

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Patients should avoid self-sourcing or using it without clinical guidance

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Interestingly, these pharmacological concentrations align closely with peak levels of endogenous GLP-1 observed during intense physiological stimulation [120, 121]

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