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A double-blind, placebo-controlled study published in the Journal of Pakistan Association of Dermatologists found that 1,200 mg of intravenous glutathione administered twice a week for 6 weeks resulted in visible skin tone lightening in 37.5% of participants

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Rakoff-Nahoum, S., Paglino, J., Eslami-Varzaneh, F., Edberg, S