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In this regard, it would be interesting to evaluate if and which OS markers may directly or indirectly reflect the inadequate functioning of the KEAP1-NRF2 system in counteracting OS, and where they are already present at high levels in young adults
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These metabolites, along with others like prostaglandin E2 (PGE2) and eicosanoids, play a pivotal role in the immunosuppressive functions of MDSCs within the tumor microenvironment [39]
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