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CJC-1295 is a growth hormone releasing hormone analog that works at a different receptor and sustains the underlying signal
Rather than replacing lifestyle interventions, GLP-1 RAs may enhance their impactby increasing satiety, reducing compulsive urges, and possibly improving cognitive control
In the ATTAIN-1 trial, it produced about 11.1% mean weight loss at 72 weeks regardless of adherence, and 12.4% among completers (Eli Lilly ATTAIN program, 2026)
These medicines work by mimicking the action of naturally occurring GLP-1, an incretin hormone released by the intestine in response to food intake
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