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Contact your healthcare provider if you experience amenorrhea (complete absence of periods for 3+ months if not menopausal), very heavy bleeding requiring hourly pad changes, severe cramping beyond your normal pattern, or intermenstrual bleeding that persists beyond the first few months

Quantitatively, the LSc represents an area with some of the highest numbers of GLP-1Rs (12, 53), but here the GLP-1R expression is predominantly on neuronal projections, which could explain the lack of activation in this region

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