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In the brains of B-Sod2/, the potently downregulated expression of GLT-1 could induce a resultant increase in the glutamate concentration at synapse, leading to excitotoxicity

10.1007/s13238-020-00789-5 Protein Cell 47 KrafftP

Finally, in vitro work has looked at cellular signaling downstream of 3-AR engagement, providing mechanistic support for the lipolysis-without-hyperglycemia profile that investigators consistently observe