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Figure 6 Weight loss 5, 10, 15, 20, 25% Participants receiving different doses of tirzepatide showed a weight loss 5, 10%, or 15%, compared with GLP-1 RAs, placebo, and insulin in a meta-analysis

Mariana, M., & Cairrao, E

Front Endocrinol (Lausanne) 2023;14:1050049

230 In summary, these findings underscore the significant role of lactylation in regulating metabolism, epigenetics, immunosuppression, cell death, stemness, and invasion and metastasis of cancer cells, offering valuable insights into the molecular mechanisms through which lactylation governs cancers and paving the way for the development of cancer intervention strategies that target lactylation