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Furthermore, the diversity and complexity of Trx1 target proteins are highlighted by the identification of 112 Trx1 target proteins in mouse primary cortical neurons, with 77 of these Trx1-interacting proteins being modulated by rapamycin (80)
(PubMed) Zhang M, Robitaille L, Eintracht S, Hoffer LJ
A 2012 study found that targeting TERC with an siRNA reduced telomerase activity by more than 50% and resulted in decreased viability of immortal cancer cells
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