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When higher levels of acetaminophen are ingested, the livers supply of glutathione is depleted and NAPQI causes liver damage.[ref] Related article: Genetic variants that increase the risk of liver damage from acetaminophen Studies on the impacts of low glutathione levels: Glutathione levels in the body are fairly tightly regulated, and balance is key
Toxic overload is a capacity problem as much as an exposure problem
The severity of colon mucosal damage was evaluated using the colonic mucosal damage index (CMDI) following the criteria outlined by Jiang et al
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