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any gout flare-ups might necessitate re-evaluation of niacinamide therapy
Strongest human evidence The METAOD006 (OPTIONS) Phase 2b trial randomized 502 adults with obesity (BMI 30-45 kg/m^2) to oral AOD-9604 (0.25, 0.5, or 1 mg/day) or placebo for 24 weeks alongside a supervised diet and exercise program
Lyophilised (freeze-dried) peptide compounds used in clinical trials must be reconstituted with a sterile diluent before administration
Some people report a temporary sensation of pressure or flushing if lipotropic therapy is administered too quickly
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