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Tanday et al ., (2022) have since described a role for Y1-R agonism in inducing periods of -cell rest that, when combined with GLP-1R agonism, proved beneficial in obesity-driven models of diabetes

For some, GLP-1 medications may help reduce food noise the constant preoccupation with food by increasing feelings of fullness and make food less rewarding

Patients should not discontinue semaglutide due to UTI concerns without consulting their prescribing physician, as the metabolic benefits typically outweigh any theoretical indirect risks