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These cells execute cytotoxicity by secreting perforin and granzyme B and releasing cytokines such as IFN- and TNF- ( Early studies reported activated CD8 + T cell infiltration at the dermal-epidermal junction in vitiligo lesions ( + T cells, DCs, and NK cells ( + T cell numbers in affected areas, with little to no presence in normal skin ( + antibodies, have emerged as significant strategies for vitiligo treatment
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