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AOD9604, when injected in saline, may be rapidly cleared from the joint due to uptake into local circulation, limiting its therapeutic effects
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The phase 2 Exenatide PD2 trial reported a 3.5-point improvement on the Movement Disorder Society Unified Parkinsons Disease Rating Scale part III (MDS UPDRS Part III), and the benefit lasted through a 12-week washout, which suggested possible disease modification
Data were normalized to cell count and expressed as pmol O/(s* Mill)
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