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Complete symptom resolution, particularly for neurological complications, can take 318 months of regular treatment depending on deficiency severity
In some cases, injection near the affected tissue may be considered
PMID 25199894
It is important to note that in BRCA1-deficient mammary cells, activation of NRF2 via small interfering RNA inhibition of KEAP1 rescued the survival defect linked with loss of BRCA1 and caused ROS levels restoration, indicating that this mechanism is important (237, 240)
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