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However, whether and how lipofuscin contributes to the development of liver fibrosis remains unknown

In addition to physical health complications, obesity is also associated with mental health challenges, including depression, anxiety, and social stigma, further exacerbating the burden on affected individuals.[10] Although lifestyle interventions are a cornerstone of clinical treatments for obesity, traditional weight-loss strategies, such as calorie restriction and increased physical activity, have shown limited long-term success.[11] Many individuals struggle to maintain weight loss due to biological mechanisms that regulate appetite and metabolism, which often drive the body to regain lost weight