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If tirzepatide remains ineffective despite optimization of all modifiable factors, alternative GLP-1 receptor agonists or other weight management medications may be considered
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( Reference Sestili, Martinelli and Bravi 35 ) also demonstrated that creatine has a direct antioxidant activity on cultured cells exposed to different oxidative agents
Co-IP and split-luciferase assays Co-IP assays were performed as previously described 50
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