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Cancer Res Treat 50(2):445460
Seek urgent advice if you experience symptoms of lactic acidosis (a rare but serious complication associated with metformin), including unusual muscle pain, difficulty breathing, severe nausea or vomiting, abdominal pain, feeling extremely weak or tired, or unusual sleepiness
Lixisenatide (Adlyxin in U.S., Lyxumia in EU): (EU approval 2013, US in 2016)
More significant changes to body composition, such as increased lean body mass and fat loss, typically become apparent after three to six months of consistent use
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