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CRBN intracellular target engagement assay An Echo acoustic liquid handler (Labcyte) was used to transfer drug in a ten-point doseresponse series (100-nl transfers) to empty wells on a white, tissue-culture-treated 384-well plate
Most community protocols use 3-6 cycles (one cycle = 3 days on, 4 days off) per course, with 3-6 months rest between courses
NAD+ Nicotinamide adenine dinucleotide, or NAD+, is a coenzyme involved in hundreds of cellular reactions
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