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Integrins have been shown to express in many mesenchymal cells and are required for homing stem progenitor cells to fracture sites for bone repair [53]
The key difference is cost: PlexusDx is $189/mo month-to-monthnth flat rate versus branded $900-1,200 monthly, making it accessible across all 50 states without insurance
Omega-3 fatty acids EPA and DHA from fish oil have well-documented anti-inflammatory and neuroprotective properties
The useful analytical framework is to ask: what is the net present value of revenues the innovator can defend after patent expiry, given realistic lifecycle management success rates, biosimilar/generic competition timelines, and payer formulary dynamics
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