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Preproglucagon is a 160-amino acid precursor encoded by the GCG gene and expressed in pancreatic -cells, intestinal cells
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The peptide influences laminin-5 (LN-5) expression in a temporally sophisticated mannerinitially inhibiting LN-5 to promote cellular proliferation and differentiation, then upregulating LN-5 expression during middle and late healing stages to improve the matrix environment and promote epidermal cell migration
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