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Strategies for this period: eat to satiety with keto-appropriate foods rather than trying to restrict calories further, increase fat intake slightly to enhance satiety, prioritize sleep because sleep deprivation amplifies hunger, maintain or increase exercise intensity to support metabolic rate, and reach out to a support community or accountability partner because the psychological transition is as challenging as the physiological one
This was not possible for the in vitro and in vivo studies, as these experiments were performed by individual investigators who were aware of the experimental groups and treatment outcome
Tierney, E
Moreover, an oral GLP-1 and amylin co-agonist (amycretin) is also in early phase clinical trials (Table 1)
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