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Semaglutide is generally not used in people with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2
A Lys34Arg substitution leaves a single lysine available, so acylation occurs site-specifically at Lys26
Electrolyte shifts, especially low sodium or potassium after repeated vomiting or diarrhea, can also cause lightheadedness and should not be overlooked when a patient reports persistent symptoms
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