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They are prescription medications intended for individuals who meet specific criteria, generally a BMI of 30 or greater, or a BMI of 27 or greater with a weight-related health issue like high blood pressure or high cholesterol

3.2 Bipolar disorder (BD) Research has shown that people suffering from BD have an altered gut microbiome with much reduced amounts of useful organisms, such as Faecalibacterium , and increased amounts of potentially harmful taxa, such as Actinobacteria, which is featured as one of the alterations (Painold et al., 2019)

Across these studies, weight loss was consistently greater with semaglutide than with placebo, and the weight loss was associated with improvements in cardiometabolic risk factors including blood pressure, waist circumference, lipid profiles, and inflammatory markers